Preventing Crisis in Cardiology Care: Roadmap to the Future

Presented by the Johns Hopkins University School of Medicine.

ACKNOWLEDGEMENT
Supported by educational grants from Boehringer Ingelheim Pharmaceuticals, Inc., Daiichi Sankyo, Inc. and Lilly USA, LLC, Abbott Laboratories, Novo Nordisk Inc., Astellas, AstraZeneca, and St. Jude Medical Inc.

TUITION
Complimentary

DATE OF RELEASE/EXPIRATION
Live sessions will be available December 7, 2011 from 9:00 AM-4:00 PM (EST) and December 8, 2011 from 9:00 AM-5:00 PM (EST).

ESTIMATED TIME TO COMPLETE
Each activity will take approximately one hour to complete, for a total of 12.0 hours.

ACTIVITY DIRECTORS
Dr. Roger Blumenthal, MD, Johns Hopkins University School of Medicine and Dr. Christopher P. Cannon, MD, Harvard Medical School

ACCREDITATION STATEMENT
The Johns Hopkins University School of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

CREDIT DESIGNATION STATEMENTS
The Johns Hopkins University School of Medicine designates this live activity for a maximum of 12.0 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

OTHER CREDITS
American Nurses Credentialing Center (ANCC) accepts AMA PRA Category 1 Credit™ from organizations accredited by the ACCME.

American Academy of Nurse Practitioners (AANP) accepts AMA PRA Category 1 Credit™ from organizations accredited by the ACCME.

American Academy of Physician Assistants (AAPA) accepts certificates of participation for educational activities certified for AMA PRA Category 1 Credit™ from organizations accredited by the ACCME. Physician assistants may receive a maximum of 12.0 hours of credit for completing this program.

JOHNS HOPKINS STATEMENT OF RESPOSIBILITY
The Johns Hopkins University School of Medicine takes responsibility for the content, quality, and scientific integrity of this CME activity.

INTENDED AUDIENCE
This virtual congress is planned to meet the CME needs of cardiologists, electrophysiologists, primary care physicians, family and internal medicine practitioners, endocrinologists, nurses and advanced practice nurses, physician assistants, diabetes educators, pharmacists and other healthcare professionals involved in caring for patients across the spectrum of cardiovascular disease (CV).

PREREQUISITES
There are no prerequisites.

STATEMENT OF NEED
Cardiovascular diseases are among the most widespread and costly health problems facing the United States today, yet they also are among the most preventable. They account for more than one-third (34.3%) of all U.S. deaths. In 2006, of all Americans who died of cardiovascular diseases, 151,000 were younger than age 65. Heart disease and stroke also are among the leading causes of disability in the United States, with nearly 3 million people reporting disability from these causes. Here are some sobering statistics: More than 1 in 3 (81 million) U.S. adults currently live with one or more types of cardiovascular disease. An estimated 935,000 heart attacks and 795,000 strokes occur each year. Americans make more than 79 million doctor visits every year for treatment and management of cardiovascular diseases. Nearly 6 million hospitalizations occur each year because of cardiovascular diseases. Reduction in the incidence of cardiovascular diseases requires preventative measures, risk factor management, diagnostic excellence, and a thorough understanding of interventional options. Leading a healthy lifestyle—not using tobacco, being physically active, maintaining a healthy weight, and making healthy food choices—greatly reduces a person’s risk of developing heart disease or stroke. Unfortunately, strategies promoting a healthy lifestyle are not well implemented (see attachment 1: Data from Public Heath Sources – Strategies to Prevent CV Crisis). Furthermore, basic health measures may not be sufficient in patients with already established cardiovascular disease (see attachment 2: Recent Research – HDL), and persons with one or more risk factors (eg, diabetes, dyslipidemia, obstructive sleep apnea, etc.) also require proper management (see attachment 2: Recent Research – HDL) (see attachment 4: Physician Survey – Specialist Referral). In these cases, medical therapies and procedures need to be properly applied, and physicians need to be knowledgeable of these approaches (see attachment 3: Literature Review - Anticoagulant Therapies). As new treatment and diagnostic options become available for this broad disease category, they add to management complexities and controversies (see attachment 5: Medical Audit – Surveillance of Aortic Valve Stenosis) (see attachment 6: New Technique – Biomarkers in HF) (see attachment 7: Patient Survey – Treatment Adherence) (see attachment 8: Expert Opinion: Antiplatelet Therapy Challenges), which this program will also address. The need for this educational activity has been established according to ACCME standards by expert assessment of a wide range of sources, including in-depth review of relevant medical literature, analysis of available quality of care and practice gap studies, and expert opinion as reflected in the faculty members' choices of topics and content. The resulting educational activity will include fair and balanced information on relevant therapies, including efficacy, side effects, and a discussion of adverse events if warranted. It will make use of clinical data that are as up-to-date as possible, including clinical trial results recently presented at major US meetings, such as the American College of Cardiology (ACC) and American Heart Association (AHA) annual meetings, international meetings such as the International Society on Thrombosis and Haemostasis, the European Society of Cardiology, and the World Stroke Conference, and important regional meetings as well. Content will also include clinical data recently published in major peerreviewed journals and input from acknowledged experts and experienced clinicians in the fields of
cardiology, endocrinology, internal medicine and primary care.

LEARNING OBJECTIVES
After participating in this activity, the participant will demonstrate the ability to:

  • Develop and implement preventive strategies to avert the future crisis in cardiovascular care
  • Appropriately tailor medical therapies to individual needs, especially anticoagulant agents in patients with atrial fibrillation (AF)
  • Identify patients with AF that are candidates for medical procedures such as ablation or left atrial appendage occlusion
  • Apply appropriate treatments to lower LDL cholesterol and high triglyceride levels
  • Evaluate key data on new strategies to raise HDL cholesterol
  • Develop and apply effective algorithms for both medical therapy and specialist referral in the diabetes setting
  • Overcome challenges in the management of patients with heart failure to improve their survival and avoid re-hospitalizations
  • Evaluate the current guidelines on the management of acute coronary syndrome; differentiate among various antiplatelet and anticoagulant agents
  • Use various biomarkers available to predict risk and diagnose certain cardiovascular conditions; evaluate current research on novel biomarkers

 COURSE FORMAT
Live sessions are approximately one hour and will be delivered in the form of video webcasts with real-time Q&A from faculty at www.CardioCareLive.com

PRE AND POST TEST AND EVALUATION
Prior to and immediately after each presentation, participants will be presented with a series of multiple choice test questions. After each presentation participants will also be presented with an online activity evaluation. A CME certificate of credit will be issued upon successful completion, which includes a passing grade of 70% or more. Participants must document the amount of time they spent in the activity.

DISCLAIMER STATEMENT
The opinions and recommendations expressed by faculty and other experts whose input is included in this program are their own. Use of Johns Hopkins University School of Medicine name implies review of educational format design and approach. Please review the complete prescribing information of specific drugs or combination of drugs, including indications, contraindications, warnings and adverse effects before administering pharmacologic therapy to patients.

INTERNET CME POLICY
The Office of Continuing Medical Education (CME) at the Johns Hopkins University School of Medicine is committed to protecting the privacy of its members and customers. Johns Hopkins University SOM CME maintains its Internet site as an information resource and service for physicians, other health professionals and the public. Continuing Medical Education at the Johns Hopkins University School of Medicine will keep your personal and credit information confidential when you participate in a CME Internet based program. Your information will never be given to anyone outside of the Johns Hopkins University School of Medicine's CME program. CME collects only the information necessary to provide you with the services that you request.

HIPAA STATEMENT

CONFIDENTIALITY DISCLAIMER FOR CME CONFERENCE ATTENDEES

I certify that I am attending a Johns Hopkins University School of Medicine CME activity for accredited training and/or educational purposes.

I understand that while I am attending in this capacity, I may be exposed to "protected health information," as that term is defined and used in Hopkins policies and in the federal HIPAA privacy regulations(the "Privacy Regulations"). Protected health information is information about a person’s health or treatment that identifies the person.

I pledge and agree to use and disclose any of this protected health information only for the training and/or educational purposes of my visit and to keep the information confidential.

I understand that I may direct to the Johns Hopkins Privacy Officer any questions I have about my obligations under this Confidentiality Pledge or under any of the Hopkins policies and procedures and applicable laws and regulations related to confidentiality. The contact information is: Johns Hopkins Privacy Officer, telephone: 410-735-6509, e-mail: HIPAA@jhmi.edu.

“The Office of Continuing Medical Education at the Johns Hopkins University School of Medicine, as provider of this activity, has relayed information with the CME attendees/participants and certifies that the visitor is attending for training, education and/or observation purposes only.”

For CME Questions, please contact the CME Office at (410) 955-2959 or e-mail cmenet@jhmi.edu.
For CME Certificates, please call (410) 502-9634.

Johns Hopkins University School of Medicine
Office of Continuing Medical Education
Turner 20/720 Rutland Avenue
Baltimore, Maryland 21205-2195

Reviewed & Approved by:
General Counsel, Johns Hopkins Medicine (4/1/03)
Updated 4/09

Acute Coronary Syndrome Education Summit

How Do We Optimize Patient Outcomes with Antiplatelet and Anticoagulant Therapies?

Presented by the Johns Hopkins University School of Medicine.

ACKNOWLEDGEMENT
Supported by an educational grant from Daiichi/Lilly and The Medicines Co.

TUITION
Complimentary

DATE OF RELEASE/EXPIRATION
Live sessions will be available July 27, 2011 from 9:00 AM-2:00 PM (EDT). These presentations will be on-demand from July 28, 2011 to January 28, 2012 at www.CardioCareLive.com.

ESTIMATED TIME TO COMPLETE
Each activity will take approximately one hour to complete, for a total of 3.75 hours.

ACTIVITY DIRECTORS
Roger S. Blumenthal, MD, Professor of Medicine, Division of Cardiology at the Johns Hopkins University School of Medicine, Director, Johns Hopkins Ciccarone Center for the Prevention of Heart Disease.
Christopher P. Cannon, MD, Associate Physician, Brigham and Women's Hospital; Associate Professor of Medicine, Harvard Medical School

ACCREDITATION STATEMENT
The Johns Hopkins University School of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

CREDIT DESIGNATION STATEMENTS
The Johns Hopkins University School of Medicine designates this live activity for a maximum of 3.75 AMA PRA Category 1 Credits™ Physicians should claim only the credit commensurate with the extent of their participation in the activity number.

OTHER CREDITS
American Nurses Credentialing Center (ANCC) accepts AMA PRA Category 1 Credit™ from organizations accredited by the ACCME.

American Academy of Nurse Practitioners (AANP) accepts AMA PRA Category 1 Credit™ from organizations accredited by the ACCME.

American Academy of Physician Assistants (AAPA) accepts certificates of participation for educational activities certified for AMA PRA Category 1 credit™ from organizations accredited by the ACCME. Physician assistants may receive a maximum of 3.75 hours of Category 1 credit for completing this program.

JOHNS HOPKINS STATEMENT OF RESPOSIBILITY
The Johns Hopkins University School of Medicine takes responsibility for the content, quality, and scientific integrity of this CME activity.

INTENDED AUDIENCE
Cardiologists, interventional cardiologists, intensive care specialists, and internal medicine physicians involved in caring for patients with ACS will be targeted as the primary audience for this event. Secondary audiences will include healthcare providers such as primary care practitioners, family physicians, nurses, physician assistants, and pharmacists.

PREREQUISITES
There are no prerequisites.

STATEMENT OF NEED
The need for this educational activity has been established according to ACCME standards by expert assessment of a wide range of sources, including in-depth review of relevant medical literature, analysis of available quality of care and practice gap studies, and expert opinion as reflected in the faculty members' choices of topics and content. The resulting educational activity will include fair and balanced information on relevant therapies, including efficacy, side effects, and a discussion of adverse events if warranted. It will make use of clinical data that is as up-to-date as possible, including clinical trial results recently presented at major U.S. meetings, such as the American College of Cardiology, the American Heart Association, the Society of Critical Care Medicine, as well as European and international meetings such as the European Society of Cardiology, and important regional meetings. Content will also include clinical data recently published in major peer-reviewed journals and input from acknowledged experts and experienced clinicians in the fields of cardiology, interventional cardiology, intensive care, and internal medicine.

LEARNING OBJECTIVES
After participating in this activity, the participant will demonstrate the ability to:
  • Properly apply anticoagulant therapies in patients with ACS; evaluate current research on new anticoagulant strategies
  • Apply guidelines' recommendations on antiplatelet therapies in patients with unstable angina and non-STEMI ACS.
  • Assess data on novel antiplatelet agents
  • Evaluate the risk of bleeding in patients with ACS
  • Assess the prognostic value of various ACS risk stratification schemes and biomarkers; select strategies, including combined approaches, to improve outcomes' prognosis

Full Disclosure Policy Affecting CME Activities
As a provider approved by the Accreditation Council for Continuing Medical Education (ACCME), it is the policy of the Johns Hopkins University School of Medicine Office of Continuing Medical Education (OCME) to require signed disclosure of the existence of financial relationships with industry from any individual in a position to control the content of a CME activity sponsored by OCME.  Members of the Planning Committee are required to disclose all relationships regardless of their relevance to the content of the activity.  Faculty are required to disclose only those relationships that are relevant to their specific presentation.  The following relationships have been reported for this activity:

FACULTY NAME AND LECTURE TITLE(S)

RELATIONSHIP(S):

Stephen D. Wiviott, MD
Antiplatelet Treatment: Applying the Guidelines and Incorporating New Therapies in UA and NSTEMI Practice

Research Funding: Eli Lilly, Daiichi Sankyo, Merck/Schering-Plough

Consultant: Sanofi, Bristol-Myers Squibb, Portola, AstraZeneca, Medco, ARENA

Deepak Bhatt, MD
Antiplatelet Treatment: Applying the Guidelines and Incorporating New Therapies in UA and NSTEMI Practice

Research Funding: Astra Zeneca, Bristol-Myers Squibb, Eisai, Sanofi, The Medicines Company

Marc Sabatine, MD
Individualizing Antiplatelet and Anticoagulant Therapies in ACS Patients

Research Funding: Amgen, AstraZeneca, Bristol-Myers Squibb /Sanofi, Daiichi-Sankyo, Sanofi, Nanosphere

Consultant: Bristol-Myers Squibb /Sanofi, Daiichi-Sankyo/Lilly, Sanofi

Honorarium: Cardiovascular Research Forum, Eli Lilly

Michael Gibson, MD
Individualizing Antiplatelet and Anticoagulant Therapies in ACS Patients

Research Funding: Abbott, Angel Medical Corporation, Astra Zeneca, Atrium Medical Systems, Baxter Healthcare, Bayer Corp, FoldRx, Genentech, Inc., Johnson & Johnson Corporation, Lantheus Medical Imaging, Roche Diagnostics, Sanofi, Ikaria, Inc.,

Consultant: Angel Medical Systems, Inc., Daiichi Sankyo Company, Inc, Eli Lilly and Company, Schering Plough Corporation, The Medicines Company, Bayer Corporation, Biogen Idec, Bristol-Meyers Squibb, GlaxoSmithKline, Heartscape Technologies, Inc, ICON Medical Imaging
Ischemix, Inc., Jim Moran Heart and Vascular Research
Institute, Johnson & Johnson Corporation

Benjamin M. Scirica, MD
Challenges in Predicting the Risk of an Acute Thrombotic Event

Research Funding: Merck, Bristol-Myers Squibb, AstraZeneca, Gilead, Daiichi-Sankyo, Johnson&Johnson, Bayer Healthcare

Consultant: Gilead, Lexicon, Arena

Michelle O’Donoghue, MD
Challenges in Predicting the Risk of an Acute Thrombotic Event

Research Funding: AstraZeneca, GlaxoSmithKline, Eisai

Chris Cannon, MD
Challenges in Predicting the Risk of an Acute Thrombotic Event

Research Funding: GlaxoSmithKline, Intekrin Therapeutics, Merck, Takeda, Accumetrics, AstraZeneca

Honorarium: Pfizer, AstraZeneca

Clinical Advisor: Automedics Medical Systems

Advisory Board: Brystol Myers Squibb, Sanofi, Novartis, Alnylam

Jeff Popma, MD
Contemporary Anticoagulation Strategies in Patients With ACS

Research Grant: Medtronic, Abbot Vascular, Boston Scientific, Cadis

Consultant: AstraZeneca, Boston Scientific

Chris Cannon, MD
Contemporary Anticoagulation Strategies in Patients With ACS

Research Funding: GlaxoSmithKline, Intekrin Therapeutics, Merck, Takeda, Accumetrics, AstraZeneca

Honorarium: Pfizer, AstraZeneca

Clinical Advisor: Automedics Medical Systems

Advisory Board: Brystol Myers Squibb, Sanofi, Novartis, Alnylam

Alan Cheng, MD
Management of Heart Failure with Device Therapies and Surgery

Consultant: Biotronik

Honorarium: Boston Scientific, Medtronic, St. Jude Medical

Nicolas Musi, MD
Current Diabetes Management: State of the Art

Consultant: Merck

Richard W. Nesto, MD
Treating Diabetes in Older Patients: Challenges and Strategies

Consultant: Sanofi, Merck, Roche/Genentech

Joanne Foody, MD
Treating Diabetes in Older Patients: Challenges and Strategies

Consultant: Merck, Pfizer, Sanofi

No other faculty members have indicated that they have any financial interests or relationships with a commercial entity whose products or services are relevant to the content of their presentation(s).

PLANNER’S NAME

RELATIONSHIP(S)

Chris Cannon, MD

Research Funding: GlaxoSmithKline, Intekrin Therapeutics, Merck, Takeda, Accumetrics, AstraZeneca

Honorarium: Pfizer, AstraZeneca

Clinical Advisor: Automedics Medical Systems

Advisory Board: Brystol Myers Squibb, Sanofi Aventis, Novartis, Alnylam

No other planners have indicated that they have any financial interests or relationships with a commercial entity.
Note:? Grants to investigators at The Johns Hopkins University are negotiated and administered by the institution which receives the grants, typically through the Office of Research Administration. Individual investigators who participate in the sponsored project(s) are not directly compensated by the sponsor, but may receive salary or other support from the institution to support their effort on the project(s).

OFF-LABEL PRODUCT DISCUSSION
The following speakers have disclosed that their presentation will reference unlabeled/unapproved uses of drugs or products:


NAME AND LECTURE TITLE(S)

PRODUCT

Marc Sabatine, MD
Individualizing Antiplatelet and Anticoagulant Therapies in ACS Patients

clopidogrel, otamixaban, rivaroxaban

Yancy
Heart Failure: Where Are Now, Where Are We Going?

ivabradine

Alan Cheng
Management of Heart Failure with Device Therapies and Surgery

St. Jude Left Atrial Pressure Monitor

COURSE FORMAT
Live sessions are approximately one hour and will be delivered in the form of video webcasts with real-time Q&A from faculty at www.CardioCareLive.com

PRE AND POST TEST AND EVALUATION
Prior to and immediately after each presentation, participants will be presented with a series of multiple choice test questions. After each presentation participants will also be presented with an online activity evaluation. A CME certificate of credit will be issued upon successful completion, which includes a passing grade of 70% or more. Participants must document the amount of time they spent in the activity.

DISCLAIMER STATEMENT
The opinions and recommendations expressed by faculty and other experts whose input is included in this program are their own.  Use of Johns Hopkins University School of Medicine name implies review of educational format design and approach.  Please review the complete prescribing information of specific drugs or combination of drugs, including indications, contraindications, warnings and adverse effects before administering pharmacologic therapy to patients.

INTERNET CME POLICY
The Office of Continuing Medical Education (CME) at the Johns Hopkins University School of Medicine is committed to protecting the privacy of its members and customers. Johns Hopkins University SOM CME maintains its Internet site as an information resource and service for physicians, other health professionals and the public. Continuing Medical Education at the Johns Hopkins University School of Medicine will keep your personal and credit information confidential when you participate in a CME Internet based program. Your information will never be given to anyone outside of the Johns Hopkins University School of Medicine's CME program. CME collects only the information necessary to provide you with the services that you request.

Atrial Fibrillation Education Summit
Entering a New Era in Stroke Prevention in Atrial Fibrillation

Presented by the Johns Hopkins University School of Medicine.

ACKNOWLEDGEMENT
Supported by an educational grant from Bristol-Myers Squibb,
Pfizer, Inc. and Boehringer Ingelheim

TUITION
Complimentary

DATE OF RELEASE/EXPIRATION
Live sessions will be available June 28, 2011 from 9:00 AM-2:00 PM (EST). These presentations will be on-demand from June 30, 2011 to December 30, 2011 at www.CardioCareLive.com

ESTIMATED TIME TO COMPLETE
Each activity will take approximately one hour to complete, for a total of 3.75 hours.

ACTIVITY DIRECTORS
Roger S. Blumenthal, MD, Professor of Medicine, Division of Cardiology at the Johns Hopkins University School of Medicine, Director, Johns Hopkins Ciccarone Center for the Prevention of Heart Disease.
Christopher P. Cannon, MD, Associate Physician, Brigham and Women's Hospital; Associate Professor of Medicine, Harvard Medical School

ACCREDITATION STATEMENT
The Johns Hopkins University School of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

CREDIT DESIGNATION STATEMENTS
The Johns Hopkins University School of Medicine designates this live activity for a maximum of 3.75 AMA PRA Category 1 credits™ Physicians should claim only credit commensurate with the extent of their participation in the activity.

OTHER CREDITS
XLN11433-01 "Cardio Care Live: June 2011 - New Frontiers in Stroke Prevention in the AF Setting: A Focus on Unmet Patients' Needs"

The University of Kentucky College of Pharmacy is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education.

This knowledge-based activity have been assigned ACPE number 022-999-11-053-L01-P and will award 1.00 contact hour (0.1 CEU) of continuing pharmacy education credit in states that recognize ACPE providers.

Statements of credit will indicate hours and CEUs based on participation and will be issued online at the conclusion of the activity. Successful completion includes signing in at registration, attending the entire session for which credit is claimed, completing the activity evaluation and requesting credit online at conclusion of the activity. The College complies with the Accreditation Standards for Continuing Pharmacy Education.

American Nurses Credentialing Center (ANCC) accepts AMA PRA Category 1 credit™ from organizations accredited by the ACCME.

American Academy of Nurse Practitioners (AANP) accepts AMA PRA Category 1 credit™ from organizations accredited by the ACCME.

American Academy of Physician Assistants (AAPA) accepts certificates of participation for educational activities certified for AMA PRA Category 1 credit™ from organizations accredited by the ACCME. Physician assistants may receive a maximum of 4 hours of Category 1 credit for completing this program.


JOHNS HOPKINS STATEMENT OF RESPONSIBILITY
The Johns Hopkins University School of Medicine takes responsibility for the content, quality, and scientific integrity of this CME activity.

INTENDED AUDIENCE
Cardiologists, neurologists, internal medicine practitioners and intensive medicine specialists, involved in caring for patients with AF at risk of stroke, will be targeted as the primary audience for this event. Secondary audiences will include primary care physicians, family physicians, nurses and advanced practice nurses, physician assistants, and pharmacists.

PREREQUISITES
There are no prerequisites.

STATEMENT OF NEED
The need for this educational activity has been established according to ACCME standards by expert assessment of a wide range of sources, including in-depth review of relevant medical literature, analysis of available quality of care and practice gap studies, and expert opinion as reflected in the faculty members' choices of topics and content. The resulting educational activity will include fair and balanced information on relevant therapies, including efficacy, side effects, and a discussion of adverse events if warranted. It will make use of clinical data that is as up-to-date as possible, including clinical trial results recently presented at major U.S. meetings, such as the American College of Cardiology, the American Heart Association, the American Academy of Neurology, the American Stroke Association, as well as international meetings such as the European Society of Cardiology, and the World Stroke Conference, and important regional meetings. Content will also include clinical data recently published in major peer-reviewed journals and input from acknowledged experts and experienced clinicians in the fields of cardiology, neurology, internal medicine, geriatrics, intensive care medicine, and others.

LEARNING OBJECTIVES
After participating in this activity, the participant will demonstrate the ability to:

  • Identify the benefits and limitations of established anticoagulant therapies and develop strategies to optimally employ these treatments
  • Integrate current research data on novel anticoagulant agents and approved agents into your clinical practice to treat broader populations of AF patients
  • Perform stroke risk assessment in "real-life" cohorts of patients with AF by incorporating findings of current research on predictive stroke markers and other concomitant cardiac sources of embolism
  • Incorporate guideline recommendations into practice; describe the proper use of available anticoagulants in the AF setting

FULL DISCLOSURE POLICY AFFECTING CME ACTIVITIES
As a provider approved by the Accreditation Council for Continuing Medical Education (ACCME), it is the policy of the Johns Hopkins University School of Medicine Office of Continuing Medical Education (OCME) to require signed disclosure of the existence of financial relationships with industry from any individual in a position to control the content of a CME activity sponsored by OCME. Members of the Planning Committee are required to disclose all relationships regardless of their relevance to the content of the activity. Faculty are required to disclose only those relationships that are relevant to their specific presentation.

COURSE FORMAT
Live sessions are approximately one hour and will be delivered in the form of video webcasts with real-time Q&A from faculty at www.CardioCareLive.com

PRE AND POST TEST AND EVALUATION
Prior to and immediately after each presentation, participants will be presented with a series of multiple choice test questions. After each presentation participants will also be presented with an online activity evaluation. A CME certificate of credit will be issued upon successful completion, which includes a passing grade of 70% or more. Participants must document the amount of time they spent in the activity.

DISCLAIMER STATEMENT
The opinions and recommendations expressed by faculty and other experts whose input is included in this program are their own. Use of Johns Hopkins University School of Medicine name implies review of educational format design and approach. Please review the complete prescribing information of specific drugs or combination of drugs, including indications, contraindications, warnings and adverse effects before administering pharmacologic therapy to patients.

INTERNET CME POLICY
The Office of Continuing Medical Education (CME) at the Johns Hopkins University School of Medicine is committed to protecting the privacy of its members and customers. Johns Hopkins University SOM CME maintains its Internet site as an information resource and service for physicians, other health professionals and the public. Continuing Medical Education at the Johns Hopkins University School of Medicine will keep your personal and credit information confidential when you participate in a CME Internet based program. Your information will never be given to anyone outside of the Johns Hopkins University School of Medicine's CME program. CME collects only the information necessary to provide you with the services that you request.

FULL DISCLOSURE POLICY AFFECTING CME ACTIVITIES
As a provider approved by the Accreditation Council for Continuing Medical Education (ACCME), it is the policy of the Johns Hopkins University School of Medicine Office of Continuing Medical Education (OCME) to require signed disclosure of the existence of financial relationships with industry from any individual in a position to control the content of a CME activity sponsored by OCME.  Members of the Planning Committee are required to disclose all relationships regardless of their relevance to the content of the activity.  Faculty are required to disclose only those relationships that are relevant to their specific presentation.  The following relationships have been reported for this activity:

FACULTY NAME AND LECTURE TITLE(S)

RELATIONSHIP(S):

Michael D Ezekowitz, MD
Are We Getting Better at Identifying AF Patients at High Risk of Stroke?

Research Funding: Boehringer Ingelheim, ARYx Therapeutics, Portola, Daiichi Sankyo

Consultant:
Boehringer Ingelheim, ARYx Therapeutics, Pfizer, Sanofi Aventis, Bristol Myers Squibb, Portola, AstraZeneca, Daiichi Sankyo, Medtronics, Eisai

Joanne Foody, MD
Are We Getting Better at Identifying AF Patients at High Risk of Stroke?

Consultant: Boehringer Ingelheim

Christian Ruff, MD
New Frontiers in Stroke Prevention in the AF Setting: A Focus on Unmet Patients’ Needs

Research Funding: Merck, AstraZeneca

Consultant:
Daiichi Sankyo, Beckman Coulter

Samuel Goldhaber, MD
New Frontiers in Stroke Prevention in the AF Setting: A Focus on Unmet Patients’ Needs

Research Funding: Boehringer Ingelheim, Bristol Myers Squibb, Eisai, EKOS, Johnson & Johnson, Sanofi Aventis

Consultant:
Boehringer Ingelheim, Bristol Myers Squibb, Daiichi Sankyo, Eisai, EKOS, Medscape, Merck, Portola, Sanofi Aventis

Gregg W. Stone, MD
Keynote Address: The State of Interventional Cardiology

Consultant: Boston Scientific, Abbott Vascular, Medtronics, The Medicines Company, Eli Lilly, Bristol Myers Squibb, Sanofi Aventis, AstraZeneca

Ownership:
Micardia, Guided Delivery Systems

Roxana Mehran, MD
Clinical Perspectives in Stent Thrombosis: A Focus on Prevention and Management

Research Funding: The Medicines Company, Bristol Myers Squibb, Sanofi Aventis

Consultant:
Abbott Vascular, AstraZeneca, Regado Biosciences, Ortho McNeil Janssen

Gregg W. Stone, MD
Clinical Perspectives in Stent Thrombosis: A Focus on Prevention and Management

Consultant: Boston Scientific, Abbott Vascular, Medtronics, The Medicines Company, Eli Lilly, Bristol Myers Squibb, Sanofi Aventis, AstraZeneca

Ownership:
Micardia, Guided Delivery Systems

Eric R. Bates, MD
Optimizing Performance Measures to Improve STEMI Outcomes

Advisor: Daiichi Sankyo, Eli Lilly, Sanofi Aventis, Merck, AstraZeneca

Matthew Price, MD
Who Is at Risk of Antiplatelet Resistance: From Genetics to Clinical Relevance

Research Funding: Bristol Myers Squibb, Sanofi Aventis, Accumetrics

Consultant:
Bristol Myers Squibb, Sanofi Aventis, Daiichi Sankyo/Eli Lilly & Co., AstraZeneca, Accumetrics, The Medicines Company

Honorarium:
Daiichi Sankyo/Eli Lilly & Co., Quest Diagnostics

Deepak Bhatt, MD
Who Is at Risk of Antiplatelet Resistance: From Genetics to Clinical Relevance

Research Funding: AstraZeneca, Bristol Myers Squibb, Eisai, Sanofi Aventis, The Medicines Company

Peter H. Jones, MD
Optimizing Current Strategies With Statins: A Focus on New Evidence

Consultant: Merck, Atherotech, Genentech, Abbott

Speakers Bureau:
Merck, AstraZeneca, Abbott (all discontinued as of January 2011)

Vijay Nambi, MD
Optimizing Current Strategies With Statins: A Focus on New Evidence

Research Funding: NIH/NHLBI,

Research Collaboration (not financial):
GE, Medipattern, Tomtec

Advisory:
Abbott
National Monitor for Anthera

Howard Weintraub, MD
Moving Beyond Statin Treatment in Dyslipidemias

Advisor: AstraZeneca, Abbott, Takeda, Kowa, Novartis, Daiichi Sankyo

Honorarium:
Joslin Diabetes Center

Speakers Bureau:
Pfizer (inactive since December, 2010)

Antonio Gotto, MD
Moving Beyond Statin Treatment in Dyslipidemias

Consultant: AstraZeneca, KOWA, Merck

Advisor:
Vatera Capital, DuPont Health Advisory Board

Board of Directors:
Aegerion Pharmaceuticals, Arisaph Pharmaceuticals

Robert P. Giugliano, MD
Emerging Therapies and Their Role in Comprehensive Lipid Management

Research Funding: Amgen

Consultant:
Merck, Regeneron, Sanofi Aventis, Amgen

Honorarium:
Merck

Chris Cannon, MD
Emerging Therapies and Their Role in Comprehensive Lipid Management

Research Funding: GlaxoSmithKline, Intekrin Therapeutics, Merck, Takeda, Accumetrics, AstraZeneca

Honorarium:
Pfizer, AstraZeneca

Clinical Advisor:
Automedics Medical Systems

Advisory Board:
Brystol Myers Squibb, Sanofi Aventis, Novartis, Alnylam

Peter Kwiterovich, MD
Management of Residual Cardiovascular Risk

Research Funding: Abbott, GlaxoSmithKline, Merck, Pfizer

Advisor:
Abbott, Merck, Pfizer

Honorarium:
Abbott, Merck, Pfizer

No other faculty members have indicated that they have any financial interests or relationships with a commercial entity whose products or services are relevant to the content of their presentation(s).

PLANNER’S NAME

RELATIONSHIP(S)

Chris Cannon, MD

Research Funding: GlaxoSmithKline, Intekrin Therapeutics, Merck, Takeda, Accumetrics, AstraZeneca

Honorarium:
Pfizer, AstraZeneca

Clinical Advisor:
Automedics Medical Systems

Advisory Board:
Brystol Myers Squibb, Sanofi Aventis, Novartis, Alnylam

No other planners have indicated that they have any financial interests or relationships with a commercial entity.

Note: Grants to investigators at The Johns Hopkins University are negotiated and administered by the institution which receives the grants, typically through the Office of Research Administration. Individual investigators who participate in the sponsored project(s) are not directly compensated by the sponsor, but may receive salary or other support from the institution to support their effort on the project(s).

OFF-LABEL PRODUCT DISCUSSION
The following speakers have disclosed that their presentation will reference unlabeled/unapproved uses of drugs or products:

NAME AND LECTURE TITLE(S)
PRODUCT
Michael D Ezekowitz, MD
Are We Getting Better at Identifying AF Patients at High Risk of Stroke?
Tecarfarin,  Ximelagatran, Dabigatran,  Apixaban, Betrixaban,  Edoxaban,  Idraparinux,  Rivaroxaban,  YM150

Christian Ruff, MD
New Frontiers in Stroke Prevention in the AF Setting: A Focus on Unmet Patients’ Needs
Apixaban, Edoxaban, Betrixaban, Eribaxaban, Razaxaban, Rivaroxaban, YM150, LY517717,
TAK 442, AZD0837, MCC 977, TTP889

Gregg W. Stone, MD
Keynote Address: The State of Interventional Cardiology
MitraClip, Sapien heart valve, Resolute

Roxana Mehran, MD
Clinical Perspectives in Stent Thrombosis: A Focus on Prevention and Management
Antiplatelet agents in PCI

Matthew Price, MD
Who Is at Risk of Antiplatelet Resistance: From Genetics to Clinical Relevance
Clopidogrel, Prasugrel, Ticagrelor

William O’Neill, MD
Stents in Patients With Stable Angina: Overused or Misunderstood?
Impella

Peter H. Jones, MD
Optimizing Current Strategies With Statins: A Focus on New Evidence
Vytorin (simvastatin/ezetimibe)

Howard Weintraub, MD
Moving Beyond Statin Treatment in Dyslipidemias
Vytorin(Ezetimibe/Simvastatin), Anacetrapib, Dalcetrapib, Aleglitazar, Laropiprant,Ezetimibe, Simvastatin, Mipomerson, MTP Inhibitor

Robert P. Guigliano, MD
Emerging Therapies and Their Role in Comprehensive Lipid Management
Anacetrapib, Dalcetrapib, Torcetrapib, PCSK-9 Inhibitors

No other speakers have indicated that they intend to reference unlabeled/unapproved uses of drugs or devices.

Diabetes Education Summit

Diabetes Today: Individualized Approaches to Effective Management

Presented by the Johns Hopkins University School of Medicine

ACKNOWLEDGEMENT
Supported by an educational grant from Novo Nordisk and Lilly USA.

TUITION
Complimentary

DATE OF RELEASE/EXPIRATION
Live sessions will be available July 28, 2011 from 11:00 AM-4:00 PM (EST). These presentations will be on-demand from July 28, 2011 to January 28, 2012 at www.CardioCareLive.com

ESTIMATED TIME TO COMPLETE
Each activity will take approximately one hour to complete, for a total of 4 hours.

ACTIVITY DIRECTORS
Roger S. Blumenthal, MD, Professor of Medicine, Division of Cardiology at the Johns Hopkins University School of Medicine, Director, Johns Hopkins Ciccarone Center for the Prevention of Heart Disease.
Christopher P. Cannon, MD, Associate Physician, Brigham and Women’s Hospital; Associate Professor of Medicine, Harvard Medical School

ACCREDITATION STATEMENT

The Johns Hopkins University School of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

CREDIT DESIGNATION STATEMENTS
The Johns Hopkins University School of Medicine designates this live activity for a maximum of 4 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

OTHER CREDITS
American Nurses Credentialing Center (ANCC) accepts AMA PRA Category 1 Credit™ from organizations accredited by the ACCME.

American Academy of Nurse Practitioners (AANP) accepts AMA PRA Category 1 Credit™ from organizations accredited by the ACCME.

American Academy of Physician Assistants (AAPA) accepts certificates of participation for educational activities certified for AMA PRA Category 1 Credit™ from organizations accredited by the ACCME. Physician assistants may receive a maximum of 4 hours of Category 1 credit for completing this program.

JOHNS HOPKINS STATEMENT OF RESPOSIBILITY

The Johns Hopkins University School of Medicine takes responsibility for the content, quality, and scientific integrity of this CME activity.

INTENDED AUDIENCE

Endocrinologists, cardiologists, internal medicine practitioners, geriatricians, and family practice and primary care physicians involved in caring for diabetes patients will be targeted as the primary audience for this event. Secondary audiences will include diabetes nurses and nurse practitioners, diabetes educators, physician assistants, and pharmacists.

PREREQUISITES

There are no prerequisites.

STATEMENT OF NEED

The need for this educational activity has been established according to ACCME standards by expert assessment of a wide range of sources, including in-depth review of relevant medical literature, analysis of available quality of care and practice gap studies, and expert opinion as reflected in the faculty members' choices of topics and content. The resulting educational activity will include fair and balanced information on relevant therapies, including efficacy, side effects, and a discussion of adverse events if warranted. It will make use of clinical data that is as up-to-date as possible, including clinical trial results recently presented at major US meetings, such as those of the American Diabetes Association, the American Association of Clinical Endocrinologists, and the Endocrine Society, as well as international meetings such as the European Society of Endocrinology and important regional meetings. Content will also include clinical data recently published in major peer-reviewed journals and input from acknowledged experts and experienced clinicians in the fields of cardiology, endocrinology, internal medicine, geriatrics, family practice medicine, and others.

LEARNING OBJECTIVES

After participating in this activity, the participant will demonstrate the ability to:

  • Assess current evidence-based guidelines for diabetes management and make practice modifications that improve glycemic control as well as control of cardiovascular risk factors in diabetes patients
  • Evaluate clinical trial results on current and emerging antiglycemic therapies and make appropriate, individualized choices for diabetes patients with differing clinical characteristics
  • Institute effective management strategies for diabetes patients who are older and/or who have multiple co-morbidities
  • Develop evidence-based, long term management plans for diabetes patients that take into account patient characteristics including age, co-morbidities, length of time with the disease, self management abilities, and other important factors that may influence success in realizing glycemic goals.

Full Disclosure Policy Affecting CME Activities
As a provider approved by the Accreditation Council for Continuing Medical Education (ACCME), it is the policy of the Johns Hopkins University School of Medicine Office of Continuing Medical Education (OCME) to require signed disclosure of the existence of financial relationships with industry from any individual in a position to control the content of a CME activity sponsored by OCME.  Members of the Planning Committee are required to disclose all relationships regardless of their relevance to the content of the activity.  Faculty are required to disclose only those relationships that are relevant to their specific presentation.  The following relationships have been reported for this activity:

FACULTY NAME AND LECTURE TITLE(S)

RELATIONSHIP(S):

Stephen D. Wiviott, MD
Antiplatelet Treatment: Applying the Guidelines and Incorporating New Therapies in UA and NSTEMI Practice

Research Funding: Eli Lilly, Daiichi Sankyo, Merck/Schering-Plough

Consultant: Sanofi, Bristol-Myers Squibb, Portola, AstraZeneca, Medco, ARENA

Deepak Bhatt, MD
Antiplatelet Treatment: Applying the Guidelines and Incorporating New Therapies in UA and NSTEMI Practice

Research Funding: Astra Zeneca, Bristol-Myers Squibb, Eisai, Sanofi, The Medicines Company

Marc Sabatine, MD
Individualizing Antiplatelet and Anticoagulant Therapies in ACS Patients

Research Funding: Amgen, AstraZeneca, Bristol-Myers Squibb /Sanofi, Daiichi-Sankyo, Sanofi, Nanosphere

Consultant: Bristol-Myers Squibb /Sanofi, Daiichi-Sankyo/Lilly, Sanofi

Honorarium: Cardiovascular Research Forum, Eli Lilly

Michael Gibson, MD
Individualizing Antiplatelet and Anticoagulant Therapies in ACS Patients

Research Funding: Abbott, Angel Medical Corporation, Astra Zeneca, Atrium Medical Systems, Baxter Healthcare, Bayer Corp, FoldRx, Genentech, Inc., Johnson & Johnson Corporation, Lantheus Medical Imaging, Roche Diagnostics, Sanofi, Ikaria, Inc.,

Consultant: Angel Medical Systems, Inc., Daiichi Sankyo Company, Inc, Eli Lilly and Company, Schering Plough Corporation, The Medicines Company, Bayer Corporation, Biogen Idec, Bristol-Meyers Squibb, GlaxoSmithKline, Heartscape Technologies, Inc, ICON Medical Imaging
Ischemix, Inc., Jim Moran Heart and Vascular Research
Institute, Johnson & Johnson Corporation

Benjamin M. Scirica, MD
Challenges in Predicting the Risk of an Acute Thrombotic Event

Research Funding: Merck, Bristol-Myers Squibb, AstraZeneca, Gilead, Daiichi-Sankyo, Johnson&Johnson, Bayer Healthcare

Consultant: Gilead, Lexicon, Arena

Michelle O’Donoghue, MD
Challenges in Predicting the Risk of an Acute Thrombotic Event

Research Funding: AstraZeneca, GlaxoSmithKline, Eisai

Chris Cannon, MD
Challenges in Predicting the Risk of an Acute Thrombotic Event

Research Funding: GlaxoSmithKline, Intekrin Therapeutics, Merck, Takeda, Accumetrics, AstraZeneca

Honorarium: Pfizer, AstraZeneca

Clinical Advisor: Automedics Medical Systems

Advisory Board: Brystol Myers Squibb, Sanofi, Novartis, Alnylam

Jeff Popma, MD
Contemporary Anticoagulation Strategies in Patients With ACS

Research Grant: Medtronic, Abbot Vascular, Boston Scientific, Cadis

Consultant: AstraZeneca, Boston Scientific

Chris Cannon, MD
Contemporary Anticoagulation Strategies in Patients With ACS

Research Funding: GlaxoSmithKline, Intekrin Therapeutics, Merck, Takeda, Accumetrics, AstraZeneca

Honorarium: Pfizer, AstraZeneca

Clinical Advisor: Automedics Medical Systems

Advisory Board: Brystol Myers Squibb, Sanofi, Novartis, Alnylam

Alan Cheng, MD
Management of Heart Failure with Device Therapies and Surgery

Consultant: Biotronik

Honorarium: Boston Scientific, Medtronic, St. Jude Medical

Nicolas Musi, MD
Current Diabetes Management: State of the Art

Consultant: Merck

Richard W. Nesto, MD
Treating Diabetes in Older Patients: Challenges and Strategies

Consultant: Sanofi, Merck, Roche/Genentech

Joanne Foody, MD
Treating Diabetes in Older Patients: Challenges and Strategies

Consultant: Merck, Pfizer, Sanofi

No other faculty members have indicated that they have any financial interests or relationships with a commercial entity whose products or services are relevant to the content of their presentation(s).

PLANNER’S NAME

RELATIONSHIP(S)

Chris Cannon, MD

Research Funding: GlaxoSmithKline, Intekrin Therapeutics, Merck, Takeda, Accumetrics, AstraZeneca

Honorarium: Pfizer, AstraZeneca

Clinical Advisor: Automedics Medical Systems

Advisory Board: Brystol Myers Squibb, Sanofi Aventis, Novartis, Alnylam

No other planners have indicated that they have any financial interests or relationships with a commercial entity.
Note:? Grants to investigators at The Johns Hopkins University are negotiated and administered by the institution which receives the grants, typically through the Office of Research Administration. Individual investigators who participate in the sponsored project(s) are not directly compensated by the sponsor, but may receive salary or other support from the institution to support their effort on the project(s).

OFF-LABEL PRODUCT DISCUSSION
The following speakers have disclosed that their presentation will reference unlabeled/unapproved uses of drugs or products:


NAME AND LECTURE TITLE(S)

PRODUCT

Marc Sabatine, MD
Individualizing Antiplatelet and Anticoagulant Therapies in ACS Patients

clopidogrel, otamixaban, rivaroxaban

Yancy
Heart Failure: Where Are Now, Where Are We Going?

ivabradine

Alan Cheng
Management of Heart Failure with Device Therapies and Surgery

St. Jude Left Atrial Pressure Monitor


COURSE FORMAT

Live sessions are approximately one hour and will be delivered in the form of video webcasts with real-time Q&A from faculty at www.CardioCareLive.com

PRE AND POST TEST AND EVALUATION

Prior to and immediately after each presentation, participants will be presented with a series of multiple choice test questions. After each presentation participants will also be presented with an online activity evaluation. A CME certificate of credit will be issued upon successful completion, which includes a passing grade of 70% or more. Participants must document the amount of time they spent in the activity.

DISCLAIMER STATEMENT
The opinions and recommendations expressed by faculty and other experts whose input is included in this program are their own.  Use of Johns Hopkins University School of Medicine name implies review of educational format design and approach.  Please review the complete prescribing information of specific drugs or combination of drugs, including indications, contraindications, warnings and adverse effects before administering pharmacologic therapy to patients.

INTERNET CME POLICY
The Office of Continuing Medical Education (CME) at the Johns Hopkins University School of Medicine is committed to protecting the privacy of its members and customers.  Johns Hopkins University SOM CME maintains its Internet site as an information resource and service for physicians, other health professionals and the public.  Continuing Medical Education at the Johns Hopkins University School of Medicine will keep your personal and credit information confidential when you participate in a CME Internet based program.  Your information will never be given to anyone outside of the Johns Hopkins University School of Medicine’s CME program.  CME collects only the information necessary to provide you with the services that you request.

Heart Failure Education Summit

Evaluating Progress in Heart Failure

Presented by the Johns Hopkins University School of Medicine

ACKNOWLEDGEMENT
Supported by an educational grant from Boston Scientific, GE Healthcare and Thoratec.

TUITION
Complimentary

DATE OF RELEASE/EXPIRATION
Live sessions will be available July 27, 2011 from 2:00 PM-3:30 PM (EST).

ACTIVITY DIRECTORS
Roger S. Blumenthal, MD, Professor of Medicine, Division of Cardiology at the Johns Hopkins University School of Medicine, Director, Johns Hopkins Ciccarone Center for the Prevention of Heart Disease.
Christopher P. Cannon, MD, Associate Physician, Brigham and Women’s Hospital; Associate Professor of Medicine, Harvard Medical School

ACCREDITATION STATEMENT

The Johns Hopkins University School of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

CREDIT DESIGNATION STATEMENTS
The Johns Hopkins University School of Medicine designates this live activity for a maximum of 1.5 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

OTHER CREDITS
American Nurses Credentialing Center (ANCC) accepts AMA PRA Category 1 Credit™ from organizations accredited by the ACCME.

American Academy of Nurse Practitioners (AANP) accepts AMA PRA Category 1 Credit™ from organizations accredited by the ACCME.

American Academy of Physician Assistants (AAPA) accepts certificates of participation for educational activities certified for AMA PRA Category 1 Credit™ from organizations accredited by the ACCME. Physician assistants may receive a maximum of 1.5 hours of Category 1 credit for completing this program.

JOHNS HOPKINS STATEMENT OF RESPOSIBILITY

The Johns Hopkins University School of Medicine takes responsibility for the content, quality, and scientific integrity of this CME activity.

INTENDED AUDIENCE

Cardiologists, interventional cardiologists, intensive care specialists, heart failure specialists, internal medicine physicians, and cardio-thoracic surgeons involved in caring for patients with heart failure, will be targeted as the primary audience for this event. Secondary audiences will include primary care practitioners, family physicians, diabetologists, nurses, physician assistants, and pharmacists.

PREREQUISITES

There are no prerequisites.

STATEMENT OF NEED

The need for this educational activity has been established according to ACCME standards by expert assessment of a wide range of sources, including in-depth review of relevant medical literature, analysis of available quality of care and practice gap studies, and expert opinion as reflected in the faculty members' choices of topics and content. The resulting educational activity will include fair and balanced information on relevant therapies, including efficacy, side effects, and a discussion of adverse events if warranted. It will make use of clinical data that is as up-to-date as possible, including clinical trial results recently presented at major U.S. meetings, such as the American College of Cardiology, the American Heart Association, the Heart Failure Society of America, as well as European and international meetings such as the European Society of Cardiology and the International Society of Cardiomyopathy and Heart Failure, and important regional meetings. Content will also include clinical data recently published in major peer-reviewed journals and input from acknowledged experts and experienced clinicians in the fields of cardiology, interventional cardiology, intensive care, and internal medicine.

LEARNING OBJECTIVES
After participating in this activity, the participant will demonstrate the ability to:

  • Discuss the use of biomarkers to guide management of heart failure
  • Evaluate recommendations of the updated guidelines on medical management of heart failure
  • Assess the use of device therapies for heart failure patients and progress in this area
  • Identify patients who could benefit from mechanical circulatory support
  • Evaluate the potential for recent research on myocyte biology to transform disease management in patients with heart failure
  • Review current tests used to assess heart failure risk and prognosis, including imaging studies and application of biomarkers
  • Identify new approaches to treatment of patients with heart failure using pharmacotherapy
  • Identify the impact of comorbidities in patients with heart failure

Full Disclosure Policy Affecting CME Activities
As a provider approved by the Accreditation Council for Continuing Medical Education (ACCME), it is the policy of the Johns Hopkins University School of Medicine Office of Continuing Medical Education (OCME) to require signed disclosure of the existence of financial relationships with industry from any individual in a position to control the content of a CME activity sponsored by OCME.  Members of the Planning Committee are required to disclose all relationships regardless of their relevance to the content of the activity.  Faculty are required to disclose only those relationships that are relevant to their specific presentation.  The following relationships have been reported for this activity:

FACULTY NAME AND LECTURE TITLE(S)

RELATIONSHIP(S):

Stephen D. Wiviott, MD
Antiplatelet Treatment: Applying the Guidelines and Incorporating New Therapies in UA and NSTEMI Practice

Research Funding: Eli Lilly, Daiichi Sankyo, Merck/Schering-Plough

Consultant: Sanofi, Bristol-Myers Squibb, Portola, AstraZeneca, Medco, ARENA

Deepak Bhatt, MD
Antiplatelet Treatment: Applying the Guidelines and Incorporating New Therapies in UA and NSTEMI Practice

Research Funding: Astra Zeneca, Bristol-Myers Squibb, Eisai, Sanofi, The Medicines Company

Marc Sabatine, MD
Individualizing Antiplatelet and Anticoagulant Therapies in ACS Patients

Research Funding: Amgen, AstraZeneca, Bristol-Myers Squibb /Sanofi, Daiichi-Sankyo, Sanofi, Nanosphere

Consultant: Bristol-Myers Squibb /Sanofi, Daiichi-Sankyo/Lilly, Sanofi

Honorarium: Cardiovascular Research Forum, Eli Lilly

Michael Gibson, MD
Individualizing Antiplatelet and Anticoagulant Therapies in ACS Patients

Research Funding: Abbott, Angel Medical Corporation, Astra Zeneca, Atrium Medical Systems, Baxter Healthcare, Bayer Corp, FoldRx, Genentech, Inc., Johnson & Johnson Corporation, Lantheus Medical Imaging, Roche Diagnostics, Sanofi, Ikaria, Inc.,

Consultant: Angel Medical Systems, Inc., Daiichi Sankyo Company, Inc, Eli Lilly and Company, Schering Plough Corporation, The Medicines Company, Bayer Corporation, Biogen Idec, Bristol-Meyers Squibb, GlaxoSmithKline, Heartscape Technologies, Inc, ICON Medical Imaging
Ischemix, Inc., Jim Moran Heart and Vascular Research
Institute, Johnson & Johnson Corporation

Benjamin M. Scirica, MD
Challenges in Predicting the Risk of an Acute Thrombotic Event

Research Funding: Merck, Bristol-Myers Squibb, AstraZeneca, Gilead, Daiichi-Sankyo, Johnson&Johnson, Bayer Healthcare

Consultant: Gilead, Lexicon, Arena

Michelle O’Donoghue, MD
Challenges in Predicting the Risk of an Acute Thrombotic Event

Research Funding: AstraZeneca, GlaxoSmithKline, Eisai

Chris Cannon, MD
Challenges in Predicting the Risk of an Acute Thrombotic Event

Research Funding: GlaxoSmithKline, Intekrin Therapeutics, Merck, Takeda, Accumetrics, AstraZeneca

Honorarium: Pfizer, AstraZeneca

Clinical Advisor: Automedics Medical Systems

Advisory Board: Brystol Myers Squibb, Sanofi, Novartis, Alnylam

Jeff Popma, MD
Contemporary Anticoagulation Strategies in Patients With ACS

Research Grant: Medtronic, Abbot Vascular, Boston Scientific, Cadis

Consultant: AstraZeneca, Boston Scientific

Chris Cannon, MD
Contemporary Anticoagulation Strategies in Patients With ACS

Research Funding: GlaxoSmithKline, Intekrin Therapeutics, Merck, Takeda, Accumetrics, AstraZeneca

Honorarium: Pfizer, AstraZeneca

Clinical Advisor: Automedics Medical Systems

Advisory Board: Brystol Myers Squibb, Sanofi, Novartis, Alnylam

Alan Cheng, MD
Management of Heart Failure with Device Therapies and Surgery

Consultant: Biotronik

Honorarium: Boston Scientific, Medtronic, St. Jude Medical

Nicolas Musi, MD
Current Diabetes Management: State of the Art

Consultant: Merck

Richard W. Nesto, MD
Treating Diabetes in Older Patients: Challenges and Strategies

Consultant: Sanofi, Merck, Roche/Genentech

Joanne Foody, MD
Treating Diabetes in Older Patients: Challenges and Strategies

Consultant: Merck, Pfizer, Sanofi

No other faculty members have indicated that they have any financial interests or relationships with a commercial entity whose products or services are relevant to the content of their presentation(s).

PLANNER’S NAME

RELATIONSHIP(S)

Chris Cannon, MD

Research Funding: GlaxoSmithKline, Intekrin Therapeutics, Merck, Takeda, Accumetrics, AstraZeneca

Honorarium: Pfizer, AstraZeneca

Clinical Advisor: Automedics Medical Systems

Advisory Board: Brystol Myers Squibb, Sanofi Aventis, Novartis, Alnylam

No other planners have indicated that they have any financial interests or relationships with a commercial entity.
Note:? Grants to investigators at The Johns Hopkins University are negotiated and administered by the institution which receives the grants, typically through the Office of Research Administration. Individual investigators who participate in the sponsored project(s) are not directly compensated by the sponsor, but may receive salary or other support from the institution to support their effort on the project(s).

OFF-LABEL PRODUCT DISCUSSION
The following speakers have disclosed that their presentation will reference unlabeled/unapproved uses of drugs or products:


NAME AND LECTURE TITLE(S)

PRODUCT

Marc Sabatine, MD
Individualizing Antiplatelet and Anticoagulant Therapies in ACS Patients

clopidogrel, otamixaban, rivaroxaban

Yancy
Heart Failure: Where Are Now, Where Are We Going?

ivabradine

Alan Cheng
Management of Heart Failure with Device Therapies and Surgery

St. Jude Left Atrial Pressure Monitor



COURSE FORMAT

Live sessions are approximately one hour and will be delivered in the form of video webcasts with real-time Q&A from faculty at www.CardioCareLive.com

PRE AND POST TEST AND EVALUATION

Prior to and immediately after each presentation, participants will be presented with a series of multiple choice test questions. After each presentation participants will also be presented with an online activity evaluation. A CME certificate of credit will be issued upon successful completion, which includes a passing grade of 70% or more. Participants must document the amount of time they spent in the activity.

 

DISCLAIMER STATEMENT
The opinions and recommendations expressed by faculty and other experts whose input is included in this program are their own.  Use of Johns Hopkins University School of Medicine name implies review of educational format design and approach.  Please review the complete prescribing information of specific drugs or combination of drugs, including indications, contraindications, warnings and adverse effects before administering pharmacologic therapy to patients.

INTERNET CME POLICY
The Office of Continuing Medical Education (CME) at the Johns Hopkins University School of Medicine is committed to protecting the privacy of its members and customers.  Johns Hopkins University SOM CME maintains its Internet site as an information resource and service for physicians, other health professionals and the public.  Continuing Medical Education at the Johns Hopkins University School of Medicine will keep your personal and credit information confidential when you participate in a CME Internet based program.  Your information will never be given to anyone outside of the Johns Hopkins University School of Medicine’s CME program.  CME collects only the information necessary to provide you with the services that you request.

Interventional Cardiology Education Summit
The First Line Defense in Heart Disease: Interventional Cardiology in Action

Presented by the Johns Hopkins University School of Medicine.

ACKNOWLEDGEMENT
Supported by an educational grant from Daiichi Sankyo/Lilly and Boston Scientific.

TUITION
Complimentary

DATE OF RELEASE/EXPIRATION
Live sessions will be available June 28, 2011 from 2:00-7:00 PM (EST). These presentations will be on-demand from June 30, 2011 to December 30, 2011 at www.CardioCareLive.com

ESTIMATED TIME TO COMPLETE
Each activity will take approximately one hour to complete, for a total of 4 hours.

ACTIVITY DIRECTORS
Roger S. Blumenthal, MD, Professor of Medicine, Division of Cardiology at the Johns Hopkins University School of Medicine, Director, Johns Hopkins Ciccarone Center for the Prevention of Heart Disease.

ACCREDITATION STATEMENT
The Johns Hopkins University School of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

CREDIT DESIGNATION STATEMENTS
The Johns Hopkins University School of Medicine designates this live activity for a maximum of 4 AMA PRA Category 1 credits™ Physicians should claim only credit commensurate with the extent of their participation in the activity number.

OTHER CREDITS
American Nurses Credentialing Center (ANCC) accepts AMA PRA Category 1 credit™ from organizations accredited by the ACCME.

American Academy of Nurse Practitioners (AANP) accepts AMA PRA Category 1 credit™ from organizations accredited by the ACCME.

American Academy of Physician Assistants (AAPA) accepts certificates of participation for educational activities certified for AMA PRA Category 1 credit™ from organizations accredited by the ACCME. Physician assistants may receive a maximum of 4 hours of Category 1 credit for completing this program.

JOHNS HOPKINS STATEMENT OF RESPOSIBILITY
The Johns Hopkins University School of Medicine takes responsibility for the content, quality, and scientific integrity of this CME activity.

INTENDED AUDIENCE
Cardiologists, interventional cardiologists, cardiac surgeons, and internal medicine physicians will be targeted as the primary audience for this event. Secondary audiences will include primary care practitioners, family physicians, nurses, physician assistants, and pharmacists.

PREREQUISITES
There are no prerequisites.

STATEMENT OF NEED
The need for this educational activity has been established according to ACCME standards by expert assessment of a wide range of sources, including in-depth review of relevant medical literature, analysis of available quality of care and practice gap studies, and expert opinion as reflected in the faculty members' choices of topics and content. The resulting educational activity will include fair and balanced information on relevant medical procedures and therapies, including outcomes, efficacy, side effects, and a discussion of adverse events if warranted. It will make use of clinical data that are as up-to-date as possible, including clinical trial results recently presented at major U.S. meetings, such as the American College of Cardiology and the American Heart Association, as well as European and international meetings such as the European Society of Cardiology and the International Academy of Cardiology, and important regional meetings. Content will also include clinical data recently published in major peer-reviewed journals and input from acknowledged experts and experienced clinicians in the fields of cardiology, interventional cardiology, cardiac surgery, and others.

LEARNING OBJECTIVES
After participating in this activity, the participant will demonstrate the ability to:

  • Evaluate the risk of stent thrombosis in various patient populations receiving either DES or BMS; develop effective strategies to minimize the frequency of thrombotic events after stenting
  • Outline new performance measures for STEMI and integrate them into clinical practice when applicable; design and implement effective processes to improve key measures
  • Investigate mechanisms for anti-platelet resistance; profile treatment options for patient who develop resistance to anti-platelet agents
  • Identify benefits and risks of stenting in patients with stable angina

FULL DISCLOSURE POLICY AFFECTING CME ACTIVITIES
As a provider approved by the Accreditation Council for Continuing Medical Education (ACCME), it is the policy of the Johns Hopkins University School of Medicine Office of Continuing Medical Education (OCME) to require signed disclosure of the existence of financial relationships with industry from any individual in a position to control the content of a CME activity sponsored by OCME. Members of the Planning Committee are required to disclose all relationships regardless of their relevance to the content of the activity. Faculty are required to disclose only those relationships that are relevant to their specific presentation.

COURSE FORMAT
Live sessions are approximately one hour and will be delivered in the form of video webcasts with real-time Q&A from faculty at www.CardioCareLive.com

PRE AND POST TEST AND EVALUATION
Prior to and immediately after each presentation, participants will be presented with a series of multiple choice test questions. After each presentation participants will also be presented with an online activity evaluation. A CME certificate of credit will be issued upon successful completion, which includes a passing grade of 70% or more. Participants must document the amount of time they spent in the activity.

DISCLAIMER STATEMENT
The opinions and recommendations expressed by faculty and other experts whose input is included in this program are their own. Use of Johns Hopkins University School of Medicine name implies review of educational format design and approach. Please review the complete prescribing information of specific drugs or combination of drugs, including indications, contraindications, warnings and adverse effects before administering pharmacologic therapy to patients.

INTERNET CME POLICY
The Office of Continuing Medical Education (CME) at the Johns Hopkins University School of Medicine is committed to protecting the privacy of its members and customers. Johns Hopkins University SOM CME maintains its Internet site as an information resource and service for physicians, other health professionals and the public. Continuing Medical Education at the Johns Hopkins University School of Medicine will keep your personal and credit information confidential when you participate in a CME Internet based program. Your information will never be given to anyone outside of the Johns Hopkins University School of Medicine's CME program. CME collects only the information necessary to provide you with the services that you request.

FULL DISCLOSURE POLICY AFFECTING CME ACTIVITIES
As a provider approved by the Accreditation Council for Continuing Medical Education (ACCME), it is the policy of the Johns Hopkins University School of Medicine Office of Continuing Medical Education (OCME) to require signed disclosure of the existence of financial relationships with industry from any individual in a position to control the content of a CME activity sponsored by OCME.  Members of the Planning Committee are required to disclose all relationships regardless of their relevance to the content of the activity.  Faculty are required to disclose only those relationships that are relevant to their specific presentation.  The following relationships have been reported for this activity:

FACULTY NAME AND LECTURE TITLE(S)

RELATIONSHIP(S):

Michael D Ezekowitz, MD
Are We Getting Better at Identifying AF Patients at High Risk of Stroke?

Research Funding: Boehringer Ingelheim, ARYx Therapeutics, Portola, Daiichi Sankyo

Consultant:
Boehringer Ingelheim, ARYx Therapeutics, Pfizer, Sanofi Aventis, Bristol Myers Squibb, Portola, AstraZeneca, Daiichi Sankyo, Medtronics, Eisai

Joanne Foody, MD
Are We Getting Better at Identifying AF Patients at High Risk of Stroke?

Consultant: Boehringer Ingelheim

Christian Ruff, MD
New Frontiers in Stroke Prevention in the AF Setting: A Focus on Unmet Patients’ Needs

Research Funding: Merck, AstraZeneca

Consultant:
Daiichi Sankyo, Beckman Coulter

Samuel Goldhaber, MD
New Frontiers in Stroke Prevention in the AF Setting: A Focus on Unmet Patients’ Needs

Research Funding: Boehringer Ingelheim, Bristol Myers Squibb, Eisai, EKOS, Johnson & Johnson, Sanofi Aventis

Consultant:
Boehringer Ingelheim, Bristol Myers Squibb, Daiichi Sankyo, Eisai, EKOS, Medscape, Merck, Portola, Sanofi Aventis

Gregg W. Stone, MD
Keynote Address: The State of Interventional Cardiology

Consultant: Boston Scientific, Abbott Vascular, Medtronics, The Medicines Company, Eli Lilly, Bristol Myers Squibb, Sanofi Aventis, AstraZeneca

Ownership:
Micardia, Guided Delivery Systems

Roxana Mehran, MD
Clinical Perspectives in Stent Thrombosis: A Focus on Prevention and Management

Research Funding: The Medicines Company, Bristol Myers Squibb, Sanofi Aventis

Consultant:
Abbott Vascular, AstraZeneca, Regado Biosciences, Ortho McNeil Janssen

Gregg W. Stone, MD
Clinical Perspectives in Stent Thrombosis: A Focus on Prevention and Management

Consultant: Boston Scientific, Abbott Vascular, Medtronics, The Medicines Company, Eli Lilly, Bristol Myers Squibb, Sanofi Aventis, AstraZeneca

Ownership:
Micardia, Guided Delivery Systems

Eric R. Bates, MD
Optimizing Performance Measures to Improve STEMI Outcomes

Advisor: Daiichi Sankyo, Eli Lilly, Sanofi Aventis, Merck, AstraZeneca

Matthew Price, MD
Who Is at Risk of Antiplatelet Resistance: From Genetics to Clinical Relevance

Research Funding: Bristol Myers Squibb, Sanofi Aventis, Accumetrics

Consultant:
Bristol Myers Squibb, Sanofi Aventis, Daiichi Sankyo/Eli Lilly & Co., AstraZeneca, Accumetrics, The Medicines Company

Honorarium:
Daiichi Sankyo/Eli Lilly & Co., Quest Diagnostics

Deepak Bhatt, MD
Who Is at Risk of Antiplatelet Resistance: From Genetics to Clinical Relevance

Research Funding: AstraZeneca, Bristol Myers Squibb, Eisai, Sanofi Aventis, The Medicines Company

Peter H. Jones, MD
Optimizing Current Strategies With Statins: A Focus on New Evidence

Consultant: Merck, Atherotech, Genentech, Abbott

Speakers Bureau:
Merck, AstraZeneca, Abbott (all discontinued as of January 2011)

Vijay Nambi, MD
Optimizing Current Strategies With Statins: A Focus on New Evidence

Research Funding: NIH/NHLBI,

Research Collaboration (not financial):
GE, Medipattern, Tomtec

Advisory:
Abbott
National Monitor for Anthera

Howard Weintraub, MD
Moving Beyond Statin Treatment in Dyslipidemias

Advisor: AstraZeneca, Abbott, Takeda, Kowa, Novartis, Daiichi Sankyo

Honorarium:
Joslin Diabetes Center

Speakers Bureau:
Pfizer (inactive since December, 2010)

Antonio Gotto, MD
Moving Beyond Statin Treatment in Dyslipidemias

Consultant: AstraZeneca, KOWA, Merck

Advisor:
Vatera Capital, DuPont Health Advisory Board

Board of Directors:
Aegerion Pharmaceuticals, Arisaph Pharmaceuticals

Robert P. Giugliano, MD
Emerging Therapies and Their Role in Comprehensive Lipid Management

Research Funding: Amgen

Consultant:
Merck, Regeneron, Sanofi Aventis, Amgen

Honorarium:
Merck

Chris Cannon, MD
Emerging Therapies and Their Role in Comprehensive Lipid Management

Research Funding: GlaxoSmithKline, Intekrin Therapeutics, Merck, Takeda, Accumetrics, AstraZeneca

Honorarium:
Pfizer, AstraZeneca

Clinical Advisor:
Automedics Medical Systems

Advisory Board:
Brystol Myers Squibb, Sanofi Aventis, Novartis, Alnylam

Peter Kwiterovich, MD
Management of Residual Cardiovascular Risk

Research Funding: Abbott, GlaxoSmithKline, Merck, Pfizer

Advisor:
Abbott, Merck, Pfizer

Honorarium:
Abbott, Merck, Pfizer

No other faculty members have indicated that they have any financial interests or relationships with a commercial entity whose products or services are relevant to the content of their presentation(s).

PLANNER’S NAME

RELATIONSHIP(S)

Chris Cannon, MD

Research Funding: GlaxoSmithKline, Intekrin Therapeutics, Merck, Takeda, Accumetrics, AstraZeneca

Honorarium:
Pfizer, AstraZeneca

Clinical Advisor:
Automedics Medical Systems

Advisory Board:
Brystol Myers Squibb, Sanofi Aventis, Novartis, Alnylam

No other planners have indicated that they have any financial interests or relationships with a commercial entity.

Note: Grants to investigators at The Johns Hopkins University are negotiated and administered by the institution which receives the grants, typically through the Office of Research Administration. Individual investigators who participate in the sponsored project(s) are not directly compensated by the sponsor, but may receive salary or other support from the institution to support their effort on the project(s).

OFF-LABEL PRODUCT DISCUSSION
The following speakers have disclosed that their presentation will reference unlabeled/unapproved uses of drugs or products:

NAME AND LECTURE TITLE(S)
PRODUCT
Michael D Ezekowitz, MD
Are We Getting Better at Identifying AF Patients at High Risk of Stroke?
Tecarfarin,  Ximelagatran, Dabigatran,  Apixaban, Betrixaban,  Edoxaban,  Idraparinux,  Rivaroxaban,  YM150

Christian Ruff, MD
New Frontiers in Stroke Prevention in the AF Setting: A Focus on Unmet Patients’ Needs
Apixaban, Edoxaban, Betrixaban, Eribaxaban, Razaxaban, Rivaroxaban, YM150, LY517717,
TAK 442, AZD0837, MCC 977, TTP889

Gregg W. Stone, MD
Keynote Address: The State of Interventional Cardiology
MitraClip, Sapien heart valve, Resolute

Roxana Mehran, MD
Clinical Perspectives in Stent Thrombosis: A Focus on Prevention and Management
Antiplatelet agents in PCI

Matthew Price, MD
Who Is at Risk of Antiplatelet Resistance: From Genetics to Clinical Relevance
Clopidogrel, Prasugrel, Ticagrelor

William O’Neill, MD
Stents in Patients With Stable Angina: Overused or Misunderstood?
Impella

Peter H. Jones, MD
Optimizing Current Strategies With Statins: A Focus on New Evidence
Vytorin (simvastatin/ezetimibe)

Howard Weintraub, MD
Moving Beyond Statin Treatment in Dyslipidemias
Vytorin(Ezetimibe/Simvastatin), Anacetrapib, Dalcetrapib, Aleglitazar, Laropiprant,Ezetimibe, Simvastatin, Mipomerson, MTP Inhibitor

Robert P. Guigliano, MD
Emerging Therapies and Their Role in Comprehensive Lipid Management
Anacetrapib, Dalcetrapib, Torcetrapib, PCSK-9 Inhibitors

No other speakers have indicated that they intend to reference unlabeled/unapproved uses of drugs or devices.

Lipid Management Education Summit
Current and Future Therapies in Lipid Management with Focus on Residual Risk Reduction

Presented by the Johns Hopkins University School of Medicine.

ACKNOWLEDGEMENT
Supported by an educational grant from Merck & Co. and Daiichi Sankyo.

TUITION
Complimentary

DATE OF RELEASE/EXPIRATION
Live sessions will be available June 29, 2011 from 11:00AM-4:00 PM (EST). These presentations will be on-demand from June 30, 2011 to December 30, 2011 at www.CardioCareLive.com

ESTIMATED TIME TO COMPLETE
Each activity will take approximately one hour to complete, for a total of 4 hours.

ACTIVITY DIRECTORS
Roger S. Blumenthal, MD, Professor of Medicine, Division of Cardiology at the Johns Hopkins University School of Medicine, Director, Johns Hopkins Ciccarone Center for the Prevention of Heart Disease.
Christopher P. Cannon, MD, Associate Physician, Brigham and Women's Hospital; Associate Professor of Medicine, Harvard Medical School

ACCREDITATION STATEMENT
The Johns Hopkins University School of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

CREDIT DESIGNATION STATEMENTS
The Johns Hopkins University School of Medicine designates this live activity for a maximum of 4 AMA PRA Category 1 credits™ Physicians should claim only credit commensurate with the extent of their participation in the activity number.

OTHER CREDITS
XLN11433-02 "Cardio Care Live: June 2011 - Optimizing Current Strategies With Statins: A Focus on New Evidence"

The University of Kentucky College of Pharmacy is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education.

This knowledge-based activity have been assigned ACPE number 022-999-11-054-L01-P and will award 1.00 contact hour (0.1 CEU) of continuing pharmacy education credit in states that recognize ACPE providers.

Statements of credit will indicate hours and CEUs based on participation and will be issued online at the conclusion of the activity. Successful completion includes signing in at registration, attending the entire session for which credit is claimed, completing the activity evaluation and requesting credit online at conclusion of the activity. The College complies with the Accreditation Standards for Continuing Pharmacy Education.

XLN11433-03 "Cardio Care Live: June 2011 - Moving Beyond Statin Treatment in Dyslipidemias"

The University of Kentucky College of Pharmacy is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education.

This knowledge-based activity have been assigned ACPE number 022-999-11-055-L01-P and will award 1.00 contact hour (0.1 CEU)  of continuing pharmacy education credit in states that recognize ACPE providers.

Statements of credit will indicate hours and CEUs based on participation and will be issued online at the conclusion of the activity. Successful completion includes signing in at registration, attending the entire session for which credit is claimed, completing the activity evaluation and requesting credit online at conclusion of the activity. The College complies with the Accreditation Standards for Continuing Pharmacy Education.

American Nurses Credentialing Center (ANCC) accepts AMA PRA Category 1 credit™ from organizations accredited by the ACCME.

American Academy of Nurse Practitioners (AANP) accepts AMA PRA Category 1 credit™ from organizations accredited by the ACCME.

American Academy of Physician Assistants (AAPA) accepts certificates of participation for educational activities certified for AMA PRA Category 1 credit™ from organizations accredited by the ACCME. Physician assistants may receive a maximum of 4 hours of Category 1 credit for completing this program.

JOHNS HOPKINS STATEMENT OF RESPOSIBILITY
The Johns Hopkins University School of Medicine takes responsibility for the content, quality, and scientific integrity of this CME activity.

INTENDED AUDIENCE
Cardiologists, internal medicine physicians, family physicians, and primary care practitioners involved in caring for patients with dyslipidemias will be targeted as the primary audience for this event. Secondary audiences will include diabetologists, nurses, physician assistants, and pharmacists.

PREREQUISITES
There are no prerequisites.

STATEMENT OF NEED
The need for this educational activity has been established according to ACCME standards by expert assessment of a wide range of sources, including in-depth review of relevant medical literature, analysis of available quality of care and practice gap studies, and expert opinion as reflected in the faculty members' choices of topics and content. The resulting educational activity will include fair and balanced information on relevant therapies, including efficacy, side effects, and a discussion of adverse events if warranted. It will make use of clinical data that is as up-to-date as possible, including clinical trial results recently presented at major U.S. meetings, such as the American College of Cardiology, the American Heart Association, the Society of General Internal Medicine, as well as European and international meetings such as the European Society of Cardiology and the International Atherosclerosis Society, and important regional meetings. Content will also include clinical data recently published in major peer-reviewed journals and input from acknowledged experts and experienced clinicians in the fields of cardiology, interventional cardiology, intensive care, and internal medicine.

LEARNING OBJECTIVES
After participating in this activity, the participant will demonstrate the ability to:
  • Evaluate safety and efficacy of non-statin therapies used in dyslipidemias; identify scenarios when non-statin treatment either alone or in combination may be particularly effective
  • Profile new mechanisms of action being developed to target dyslipidemias; review new clinical research results
  • Properly manage the residual risk; recognize the importance of increasing HDL cholesterol levels and decreasing triglyceride levels
  • Enhance compliance with statin treatment; discuss new research in this area and apply appropriate statin-based regimens in various patient populations

FULL DISCLOSURE POLICY AFFECTING CME ACTIVITIES
As a provider approved by the Accreditation Council for Continuing Medical Education (ACCME), it is the policy of the Johns Hopkins University School of Medicine Office of Continuing Medical Education (OCME) to require signed disclosure of the existence of financial relationships with industry from any individual in a position to control the content of a CME activity sponsored by OCME. Members of the Planning Committee are required to disclose all relationships regardless of their relevance to the content of the activity. Faculty are required to disclose only those relationships that are relevant to their specific presentation.

COURSE FORMAT
Live sessions are approximately one hour and will be delivered in the form of video webcasts with real-time Q&A from faculty at www.CardioCareLive.com

PRE AND POST TEST AND EVALUATION
Prior to and immediately after each presentation, participants will be presented with a series of multiple choice test questions. After each presentation participants will also be presented with an online activity evaluation. A CME certificate of credit will be issued upon successful completion, which includes a passing grade of 70% or more. Participants must document the amount of time they spent in the activity.

DISCLAIMER STATEMENT
The opinions and recommendations expressed by faculty and other experts whose input is included in this program are their own. Use of Johns Hopkins University School of Medicine name implies review of educational format design and approach. Please review the complete prescribing information of specific drugs or combination of drugs, including indications, contraindications, warnings and adverse effects before administering pharmacologic therapy to patients.

INTERNET CME POLICY
The Office of Continuing Medical Education (CME) at the Johns Hopkins University School of Medicine is committed to protecting the privacy of its members and customers. Johns Hopkins University SOM CME maintains its Internet site as an information resource and service for physicians, other health professionals and the public. Continuing Medical Education at the Johns Hopkins University School of Medicine will keep your personal and credit information confidential when you participate in a CME Internet based program. Your information will never be given to anyone outside of the Johns Hopkins University School of Medicine's CME program. CME collects only the information necessary to provide you with the services that you request.

FULL DISCLOSURE POLICY AFFECTING CME ACTIVITIES
As a provider approved by the Accreditation Council for Continuing Medical Education (ACCME), it is the policy of the Johns Hopkins University School of Medicine Office of Continuing Medical Education (OCME) to require signed disclosure of the existence of financial relationships with industry from any individual in a position to control the content of a CME activity sponsored by OCME.  Members of the Planning Committee are required to disclose all relationships regardless of their relevance to the content of the activity.  Faculty are required to disclose only those relationships that are relevant to their specific presentation.  The following relationships have been reported for this activity:

FACULTY NAME AND LECTURE TITLE(S)

RELATIONSHIP(S):

Michael D Ezekowitz, MD
Are We Getting Better at Identifying AF Patients at High Risk of Stroke?

Research Funding: Boehringer Ingelheim, ARYx Therapeutics, Portola, Daiichi Sankyo

Consultant:
Boehringer Ingelheim, ARYx Therapeutics, Pfizer, Sanofi Aventis, Bristol Myers Squibb, Portola, AstraZeneca, Daiichi Sankyo, Medtronics, Eisai

Joanne Foody, MD
Are We Getting Better at Identifying AF Patients at High Risk of Stroke?

Consultant: Boehringer Ingelheim

Christian Ruff, MD
New Frontiers in Stroke Prevention in the AF Setting: A Focus on Unmet Patients’ Needs

Research Funding: Merck, AstraZeneca

Consultant:
Daiichi Sankyo, Beckman Coulter

Samuel Goldhaber, MD
New Frontiers in Stroke Prevention in the AF Setting: A Focus on Unmet Patients’ Needs

Research Funding: Boehringer Ingelheim, Bristol Myers Squibb, Eisai, EKOS, Johnson & Johnson, Sanofi Aventis

Consultant:
Boehringer Ingelheim, Bristol Myers Squibb, Daiichi Sankyo, Eisai, EKOS, Medscape, Merck, Portola, Sanofi Aventis

Gregg W. Stone, MD
Keynote Address: The State of Interventional Cardiology

Consultant: Boston Scientific, Abbott Vascular, Medtronics, The Medicines Company, Eli Lilly, Bristol Myers Squibb, Sanofi Aventis, AstraZeneca

Ownership: Micardia, Guided Delivery Systems

Roxana Mehran, MD
Clinical Perspectives in Stent Thrombosis: A Focus on Prevention and Management

Research Funding: The Medicines Company, Bristol Myers Squibb, Sanofi Aventis

Consultant:
Abbott Vascular, AstraZeneca, Regado Biosciences, Ortho McNeil Janssen

Gregg W. Stone, MD
Clinical Perspectives in Stent Thrombosis: A Focus on Prevention and Management

Consultant: Boston Scientific, Abbott Vascular, Medtronics, The Medicines Company, Eli Lilly, Bristol Myers Squibb, Sanofi Aventis, AstraZeneca

Ownership: Micardia, Guided Delivery Systems

Eric R. Bates, MD
Optimizing Performance Measures to Improve STEMI Outcomes

Advisor: Daiichi Sankyo, Eli Lilly, Sanofi Aventis, Merck, AstraZeneca

Matthew Price, MD
Who Is at Risk of Antiplatelet Resistance: From Genetics to Clinical Relevance

Research Funding: Bristol Myers Squibb, Sanofi Aventis, Accumetrics

Consultant:
Bristol Myers Squibb, Sanofi Aventis, Daiichi Sankyo/Eli Lilly & Co., AstraZeneca, Accumetrics, The Medicines Company

Honorarium:
Daiichi Sankyo/Eli Lilly & Co., Quest Diagnostics

Deepak Bhatt, MD
Who Is at Risk of Antiplatelet Resistance: From Genetics to Clinical Relevance

Research Funding: AstraZeneca, Bristol Myers Squibb, Eisai, Sanofi Aventis, The Medicines Company

Peter H. Jones, MD
Optimizing Current Strategies With Statins: A Focus on New Evidence

Consultant: Merck, Atherotech, Genentech, Abbott

Speakers Bureau:
Merck, AstraZeneca, Abbott (all discontinued as of January 2011)

Vijay Nambi, MD
Optimizing Current Strategies With Statins: A Focus on New Evidence

Research Funding: NIH/NHLBI,

Research Collaboration (not financial):
GE, Medipattern, Tomtec

Advisory:
Abbott
National Monitor for Anthera

Howard Weintraub, MD
Moving Beyond Statin Treatment in Dyslipidemias

Advisor: AstraZeneca, Abbott, Takeda, Kowa, Novartis, Daiichi Sankyo

Honorarium:
Joslin Diabetes Center

Speakers Bureau:
Pfizer (inactive since December, 2010)

Antonio Gotto, MD
Moving Beyond Statin Treatment in Dyslipidemias

Consultant: AstraZeneca, KOWA, Merck

Advisor:
Vatera Capital, DuPont Health Advisory Board

Board of Directors:
Aegerion Pharmaceuticals, Arisaph Pharmaceuticals

Robert P. Giugliano, MD
Emerging Therapies and Their Role in Comprehensive Lipid Management

Research Funding: Amgen

Consultant:
Merck, Regeneron, Sanofi Aventis, Amgen

Honorarium:
Merck

Chris Cannon, MD
Emerging Therapies and Their Role in Comprehensive Lipid Management

Research Funding: GlaxoSmithKline, Intekrin Therapeutics, Merck, Takeda, Accumetrics, AstraZeneca

Honorarium:
Pfizer, AstraZeneca

Clinical Advisor:
Automedics Medical Systems

Advisory Board:
Brystol Myers Squibb, Sanofi Aventis, Novartis, Alnylam

Peter Kwiterovich, MD
Management of Residual Cardiovascular Risk

Research Funding: Abbott, GlaxoSmithKline, Merck, Pfizer

Advisor:
Abbott, Merck, Pfizer

Honorarium:
Abbott, Merck, Pfizer

No other faculty members have indicated that they have any financial interests or relationships with a commercial entity whose products or services are relevant to the content of their presentation(s).

PLANNER’S NAME

RELATIONSHIP(S)

Chris Cannon, MD

Research Funding: GlaxoSmithKline, Intekrin Therapeutics, Merck, Takeda, Accumetrics, AstraZeneca

Honorarium:
Pfizer, AstraZeneca

Clinical Advisor:
Automedics Medical Systems

Advisory Board:
Brystol Myers Squibb, Sanofi Aventis, Novartis, Alnylam

No other planners have indicated that they have any financial interests or relationships with a commercial entity.

Note: Grants to investigators at The Johns Hopkins University are negotiated and administered by the institution which receives the grants, typically through the Office of Research Administration. Individual investigators who participate in the sponsored project(s) are not directly compensated by the sponsor, but may receive salary or other support from the institution to support their effort on the project(s).

OFF-LABEL PRODUCT DISCUSSION
The following speakers have disclosed that their presentation will reference unlabeled/unapproved uses of drugs or products:

NAME AND LECTURE TITLE(S)
PRODUCT
Michael D Ezekowitz, MD
Are We Getting Better at Identifying AF Patients at High Risk of Stroke?
Tecarfarin,  Ximelagatran, Dabigatran,  Apixaban, Betrixaban,  Edoxaban,  Idraparinux,  Rivaroxaban,  YM150

Christian Ruff, MD
New Frontiers in Stroke Prevention in the AF Setting: A Focus on Unmet Patients’ Needs
Apixaban, Edoxaban, Betrixaban, Eribaxaban, Razaxaban, Rivaroxaban, YM150, LY517717,
TAK 442, AZD0837, MCC 977, TTP889

Gregg W. Stone, MD
Keynote Address: The State of Interventional Cardiology
MitraClip, Sapien heart valve, Resolute

Roxana Mehran, MD
Clinical Perspectives in Stent Thrombosis: A Focus on Prevention and Management
Antiplatelet agents in PCI

Matthew Price, MD
Who Is at Risk of Antiplatelet Resistance: From Genetics to Clinical Relevance
Clopidogrel, Prasugrel, Ticagrelor

William O’Neill, MD
Stents in Patients With Stable Angina: Overused or Misunderstood?
Impella

Peter H. Jones, MD
Optimizing Current Strategies With Statins: A Focus on New Evidence
Vytorin (simvastatin/ezetimibe)

Howard Weintraub, MD
Moving Beyond Statin Treatment in Dyslipidemias
Vytorin(Ezetimibe/Simvastatin), Anacetrapib, Dalcetrapib, Aleglitazar, Laropiprant,Ezetimibe, Simvastatin, Mipomerson, MTP Inhibitor

Robert P. Guigliano, MD
Emerging Therapies and Their Role in Comprehensive Lipid Management
Anacetrapib, Dalcetrapib, Torcetrapib, PCSK-9 Inhibitors

No other speakers have indicated that they intend to reference unlabeled/unapproved uses of drugs or devices.

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